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Design and Synthesis of Urazole Derivatives via Ring Closing Metathesis
Journal
ChemistrySelect
Date Issued
2022-11-11
Author(s)
Kotha, Sambasivarao
Singh, Deepshikha
Bandi, Vijayalakshmi
Abstract
An efficient and short synthetic sequence to highly functionalized urazole derivatives is reported. N-substituted-1,2,4-triazoline-3,5-dione (TAD) is a versatile synthetic reagent. Here, simple reactions such as allylation, ring-closing metathesis and hydrogenation were used successfully to construct the oxygenated urazole derivatives which may have implications in medicinal chemistry and organic synthesis.
Volume
7
Subjects