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Amine Functionalized MWCNTs Modified MIP-Based Electrode for Detection of Epicatechin in Tea
Journal
IEEE Sensors Journal
ISSN
1530437X
Date Issued
2022-06-01
Author(s)
Das, Debangana
Nag, Shreya
Adaval, Akansha
Hazarika, Ajanta Kumar
Sabhapondit, Santanu
Bhattacharyya, Arup R.
Tudu, Bipan
Bandopadhyay, Rajib
Banerjee Roy, Runu
Abstract
The present work utilizes the molecular imprinted polymer technology for the fabrication of a stable and reproducible electrode for the detection of epicatechin (EC) in tea. The polymer-graphite composite embedded with amine functionalized multi-walled carbon nanotubes (f-MWCNTs) was prepared and used as the sensing material. The sensing materials of the MIP-EC electrode were characterized by field emission gun scanning electron microscopy, transmission electron microscopy and fourier transform infrared spectroscopy. A wide linearity change from 1μM - 30μM and 30 μ - 300 μM, detection limit of 51.92 nM and quantification limit of 0.17μM were obtained with the electrode. To predict the content of EC, two linear regression models were developed, using the differential pulse voltammetry responses and high-performance liquid chromatography analysis results as reference data. Prediction accuracies of 92% using principal component regression (PCR) and 93.58% using partial least square regression (PLSR) were obtained. The root mean square error of calibration for PLSR and PCR was 0.29 and 0.31 using 6 and 10 latent variables, respectively. The stability of the electrode was found to be of approximately 90 days.
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