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A metal-free four-component sulfonylation, Giese cyclization, selenylation cascade via insertion of sulfur dioxide
Journal
Chemical Communications
ISSN
13597345
Date Issued
2022-05-23
Author(s)
Nair, Akshay M.
Halder, Indranil
Volla, Chandra M.R.
Abstract
We hereby report a highly regio- and diastereoselective arylsulfonylation-radical cyclization-selenylation cascade of alkynyl cyclohexadienones for the facile synthesis of highly functionalized dihydrochromenones. The protocol utilizes aryldiazonium salts as aryl partners and DABSO as a benign SO2 source and also as a redox mediator. Additionally, we also developed a visible light mediated protocol wherein diaryliodonium salts were used as the aryl partners at room temperature.