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Synthesis of mixed musks via Eschenmoser-Tanabe fragmentation, enyne metathesis and Diels-Alder reaction as key steps
Journal
RSC Advances
Date Issued
2022-05-11
Author(s)
Kotha, Sambasivarao
Agrawal, Arpit
Tangella, Yellaiah
Abstract
Musk analogues containing different macrocyclic ring systems as well as different annulated ring systems were synthesised by a simple and useful strategy. This strategy includes Eschenmoser-Tanabe fragmentation, enyne metathesis and Diels-Alder reaction as key steps. Starting from easily available (n) macrocyclic ketones, (n + 3) macrocyclic systems were assembled using the basic organic reactions.