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Natural biopolymeric nanomaterials for tissue engineering: Overview and recent advances
Journal
Biopolymeric Nanomaterials: Fundamentals and Applications
Date Issued
2021-01-01
Author(s)
Pawar, Vaishali
Ravi, Sneha
Srivastava, Rohit
Abstract
Tissue engineering is an interdisciplinary field that combines the principles of biomaterials, cell transplantation, and engineering, to develop functional tissue substitutes and/or promote endogenous regeneration. Naturally derived biopolymers, due to their advantages, play an important role in tissue engineering. They aid in cell adhesion, migration, proliferation, and differentiation, all of which are key steps in the repair process. The addition of nanomaterials into biopolymeric constructs assured new horizons in tissue engineering by providing multifunctionality and enhanced properties. This chapter will describe major biopolymers and their characteristic properties with main emphasis on biopolymeric nanomaterial-based tissue constructs developed using gelatin, collagen, silk, cellulose, chitosan, alginate, and hyaluronic acid for the bone, skin, organs, and cartilage tissue engineering. New developments as well as clinical status update of the biopolymeric nanomaterial-based tissue engineering constructs are also reviewed.
Subjects